LAMA2 and limb-girdle muscular dystrophy: Mutations in α2 cause two types of muscular dystrophy: Laminin α2 Congenital Muscular Dystrophy (LAMA2-CMD), also known as Merosin-Deficient Congenital Muscular Dystrophy type 1A (MDC1A)20, and Limb-Girdle Muscular Dystrophy (LGMD)21.