In glioblastoma cases from The Cancer Genome Atlas (TCGA), FGFR2 is most commonly deleted and several FGFR2 fusion genes have been identified, including CXCL17–FGFR2, SIPA1L3–FGFR2, FGFR2–SIPA1L3 and FGFR2–CEACAM1. The gene discussed is SIPA1L3; the disease is glioblastoma.