CD47 and glioblastoma: Gholamin, Mitra et al. demonstrated that when anti-CD47 (Hu5F9-G4) was combined with either irradiation or TMZ, phagocytosis of glioblastoma cells by peripheral blood mononuclear cell-derived macrophages was enhanced in vitro.420 Importantly, in vivo, the combination of RT with Hu5F9-G4 significantly improved survival in a patient-derived xenograft model of glioblastoma.426