Out of the paired samples of tumor and adjacent normalfrom lungadenocarcinoma (LUAD), lung squamous cell carcinoma (LSCC), head andneck squamous cell carcinoma (HNSCC), and clear cell renal cell carcinoma(CCRCC) studies, 5(4.9%), 4(4.2%), 5(8.2%), and 2(2.7%) patients,respectively, presented heterozygous HLA-A, HLA-B, or HLA-C genotypesin the adjacent normal samples while losing one allele in the correspondingtumor samples (Table 2). This evidence concerns the gene HLA-C and squamous cell carcinoma.