Withinthe same cancer type, the homozygosity rate is consistently the highestfor the HLA-A gene (mean = 18.9% across all nine cancers) and thelowest for the HLA-B gene (mean = 7.0%) with the biggest differencearound 15% in LUAD and HNSCC tumors. The gene discussed is HLA-A; the disease is head and neck squamous cell carcinoma.