SNCA and Parkinson disease: aimed to investigate associations between unconjugated BPA bound to human serum albumin antibodies (BPA-HSA) and alpha-synuclein antibodies and between IDP antibodies and alpha-synuclein antibodies, demonstrating that there were significant associations and risks between antibodies formed against BPA-bound-to-albumin antibodies and antibodies formed against alpha-synuclein, which with an abnormal deposition, plays a central role in the pathogenesis of disorders such as Parkinson's disease and Dementia (Kharrazian et al. 2019).