NT-proBNP: N-terminal prohormone of brain natriuretic peptide; CRIF/ORIF: closed/open reduction and internal fixation; HA: hemiarthroplasty; THA: total hip arthroplasty; CHD: coronary heart disease; COPD: chronic obstructive pulmonary disease. This evidence concerns the gene NPPB and chronic obstructive pulmonary disease.