Outcome variable: one-year mortality, Exposure variable: NT-proBNP; NT-proBNP tertiles; NT-proBNP tertiles, Non-adjusted model adjust for: none, Adjust I model adjust for: age, sex, Adjust II model adjust for: age, sex, hypertension, CHD, cancer, hepatitis, urea, creatinine, transfusion and stay in hospital. The gene discussed is NPPB; the disease is hepatitis A virus infection.