After reviewing ncRNA studies in gynecological cancers, it was found that genes include TEN, ZEB1, ZEB2, HMGA2, MACC1, TIMP2, TWIST1, MMP-9, Tiam1, EGFR, LVSI, NOB1, and mTOR have been studied as the most important genes involved in gynecological cancers. The gene discussed is MACC1; the disease is female reproductive organ cancer.