CD44 and breast carcinoma: Similar resultswere reported in MCF-7 breast cancer cells, accompanied with inhibitionof the transforming growth factor-β1-induced EMT.52 On the other hand, the accompanied subsequentactivity of HOX-1 helps maintain the expression of CD44, which explainsthe non-significant changes in CD44 in 8 μM hemin-treated cells(Figure 5F).