C3 and lobular neoplasia: Serum HA level showed similar sensitivity but lower specificity than anti-dsDNA antibody or C3 levels (sensitivity and specificity rates: 74.07% and 68.96% respectively for HA, 75.00% and 91.67% respectively for anti-dsDNA antibodies, and 62.07% and 96.43% respectively for C3), and lower sensitivity and specificity rates than proteinuria (sensitivity and specificity rates of 85.71% and 87.50% respectively) and renal SLEDAI-2K scores (sensitivity and specificity rates of 100.00% and 100.00% respectively) in distinguishing LN patients with active disease and remission (53).