cGAS-STING drives aging, senescence, anti-tumor immunity, autoimmune disease, and acute and chronic heart failure inflammatory disorders such as pancreatitis, macular degeneration, alcoholic hepatitis, cancer, metastasis, myocardial infarction, sepsis, systemic lupus erythematosus, and Parkinson's disease (116, 130). This evidence concerns the gene STING1 and cancer.