Similar to WT STm infection, genes involved in the regulation of immune responses (ATF3, BATF3, ETS2, IRF9, NFκB2, MAFA, TNFAIP3), effector functions, (CCL4, CD200L, CD40, CD72, CD80, IL18) and TLR signaling, (EAF2, TLR15, TRAF3IP2, TOLLIP) were upregulated after ΔprgH STm infection in both models (Supplementary Material 2). Here, IL18 is linked to infection.