WT and ΔprgH STm infected 2D enteroids shared 1 common gene (STEAP1) while each strain regulated 1 specific gene each, TGM4 and TLR4. WT and ΔprgH STm infection of 3D enteroids shared 27 common genes while WT STm infection regulated 4 genes, (CD83, IL6, NDNF, PKD2L1) and ΔprgH STm regulated 3 genes (ABCG2, B2M, IL8L). The gene discussed is TGM4; the disease is infection.