Mourão et al concluded that papillary thyroid carcinoma patients with low nonstimulated Tg levels (Tg < 0.3 ng/mL) and negative nodal status in the neck after thyroid surgery did not require postoperative I-131 treatment.10These patients need no cutoff of Tg level. The gene discussed is TG; the disease is thyroid gland papillary carcinoma.