SIX1 and branchio-oto-renal syndrome: Six1 is a key transcriptional regulator of many developmental processes and several single nucleotide mutations are causative for Branchio-oto-renal syndrome (BOR) and Deafness, autosomal dominant 23 (DFNA23) (reviewed in (Moody and Saint-Jeannet, 2014; Moody and LaMantia, 2015; Riddiford and Schlosser, 2016; Smith, 2018; Streit, 2018; Schlosser, 2021)).