As SLURP-1 and Oncotag influenced expression of some genes in the A431/NanoLuc tumors (Figure 4), we investigated whether it could also affect expression of miRNAs involved in skin cancer progression (Neagu et al., 2020): tumor suppressive miR-7 and miR-203 (Sonkoly et al., 2012; Horsham et al., 2015, 7), pro-oncogenic miR-21, miR-135b, and miR-221 (Yang et al., 2011; Garofalo et al., 2012; Hu et al., 2019), and miR-31 and miR-451 with context-dependent action on tumor growth (Wang et al., 2014; Yu et al., 2018; Bai and Wu, 2019; Fu et al., 2021). The gene discussed is SLURP1; the disease is neoplasm.