ITGA5 and cancer: Increased CHRNA7 and ITGA5 expression correlates with poor prognosis in patients with various types of cancer including epidermoid carcinoma (Morozevich et al., 2012; Yang et al., 2015; Hou et al., 2020; Wang et al., 2021), while elevated CERK expression correlates with breast tumor recurrence (Payne et al., 2014).