SLURP-1 expression is downregulated in primary and metastatic melanomas compared to normal cells (Bergqvist et al., 2018; Arousse et al., 2019), while elevated plasma level of SLURP-1 correlates with better survival prognosis for patients with pancreatic cancer (Throm et al., 2018). This evidence concerns the gene SLURP1 and melanoma.