One hour incubation of human epidermoid carcinoma A431 cells with recombinant SLURP-1 induces secretion of endogenous SLURP-1 from an intracellular depot, thus increasing the SLURP-1 concentration in extracellular media and overall antiproliferative effect (Lyukmanova et al., 2018). This evidence concerns the gene SLURP1 and squamous cell carcinoma.