SLURP-1 controls growth and migration of lung adenocarcinoma A549 cells via interaction with α7-nAChR heterocomplexes with EGFR or PDGFR and modulation of the PI3K/AKT/mTOR and inositol-1,4,5-trisphosphate (IP3) pathways (Shulepko et al., 2020b; Bychkov et al., 2021). The gene discussed is EGFR; the disease is lung adenocarcinoma.