Taken together, these data indicate that DNA‐damaging agent‐induced senescence in breast cancer cells leads to more robust expression of various pro‐inflammatory SASP (TGFβ1, TGFβ2, and IL‐6, CXCL2, CXCL8, CSF1) and cell surface ligands (CEACAM1, CEACAM5, PVR, and CD274) that augment pro‐tumorigenic immune responses within the TME. The gene discussed is CXCL2; the disease is breast cancer.