Importantly, GAS41 has been found to target downstream regulators such as Zinc finger E-box-binding homeobox 1 (ZEB1) [33], transforming acidic coiled-coil 1 (TACC) [34], and (Transcription elongation factor A protein 1) TCEA1 [35] to modulate cancer progression (Fig. 2). This evidence concerns the gene ZEB1 and cancer.