In the orthotopic model of pancreatic cancer Nomura et al. [44] showed that the cells pretreated with NF-κB inhibitor—BAY 11–7085 together with MYC-inhibitor—minnelide, showed decreased expression of tumor EMT-associated genes, such as Snail1/2, Zeb1, vimentin, MMP9 or N-cadherin. Here, ZEB1 is linked to familial pancreatic carcinoma.