Tripathi et al. [25] demonstrated that Rho GTPase-activating protein (RhoGAP) - Deleted in Liver Cancer 1 (DLC1), the downregulation of which is associated with prostate carcinoma (PCA), stabilizes AJs in PCA cell lines through binding to E-cadherin and as such has an inhibitory effect on NF-κB activation. This evidence concerns the gene NFKB1 and posterior cortical atrophy.