The major tumorigenic function of NF-κB has been linked to disturbed regulation of the transcription of targets associated with the cell cycle including cyclin D1/D2 and CDK 2/CDK6, and apoptosis, including cIAP1, XIAP and c-FLIP, resulting in abnormal cancer cell progression and the suppression of apoptosis respectively [2]. This evidence concerns the gene NFKB1 and cancer.