Among the four genes of prognostic characteristics, the expression levels in hepatocellular carcinoma and adjacent normal tissues were detected by qRT-PCR, EZH2, G6PD, LGALS3 and PSMD14 were all more highly expressed in HCC tumor tissues (p < 0.05) (Fig. 11A-H). This evidence concerns the gene G6PD and hepatocellular carcinoma.