The logistic regression analysis showed that the age at diagnosis, edema, RPGN, hemoglobin, platelet, albumin, systolic blood pressure, diastolic blood pressure, Bun, Scr, and eGFR at baseline were significantly different between the ESRD group (n = 68) and non-ESRD group (n = 46). The gene discussed is ALB; the disease is rapidly progressive glomerulonephritis.