The global abundance of m6A in cancer cells is critical for cancer initiation, progression, metastasis, relapse and treatment resistance [21], which is regulated by m6A writers, including methyltransferase Like 3 (METTL3), METTL14 and WT1 associated protein (WTAP), and m6A erasers, such as fat mass and obesity associated protein (FTO) and AlkB homolog (ALKBH). Here, ALKBH1 is linked to cancer.