Univariate Cox regression models were used to analyze and screen for influencing factors associated with survival in the training set.The results showed that age, race, marriage, Grade tumor grade, TNM stage, chemotherapy, RT, PSA, and GS were all prognostic factors affecting patient survival.Then, independent risk factors associated with patient survival were screened by multivariate Cox regression analysis. The gene discussed is KLK3; the disease is neoplasm.