PC has a high incidence in the elderly population, so this study used the SEER database to establish a new nomogram to predict CSS in nonsurgically treated elderly PC patients, and our results showed that age, race, marriage, PSA, GS, RT mode, chemotherapy and TNM stage are independent risk factors for elderly prostate patients 3 and 8 years. The gene discussed is KLK3; the disease is urogenital neoplasm.