The formation of a glial cell scar presents a physical impediment to axonal growth, thereby hindering the recovery of locomotor function following SCI.13,14 Prior studies have established that MLL1 exhibits robust expression in neural tissues under hypoxic conditions.15 and is critical for the growth of glioblastoma stem-like cells,16 implying a potential involvement of MLL1 in gliogenesis. The gene discussed is KMT2A; the disease is glioblastoma.