DYSF and limb-girdle muscular dystrophy: In the present study, there were variations in the prevalence of LGMD subtypes according to the ethnic background and geographic origin of the subjects, as well as based on founder mutations.3, 6, 7In a large American study8that employed a 35-gene NGS panel and examined patients with clinical suspicion of LGMD, most subjects had variants in theCAPN3(17%),DYSF(16%),FKRP(9%), andANO5(7%) genes.