Additionally, we found that the expression of signature lncRNAs in glioma may be regulated by the activator protein‐1 (AP‐1) TF family, which consists of several sub‐families: the activating transcription factor (BATF, LRF1/ATF3, JDP1, JDP2, ATF2), FOS (FOS, FOSB, FOSL1, and FOSL2), and JUN (JUN, JUNB, and JUND).52, 53. This evidence concerns the gene FOS and central nervous system cancer.