In this research, we established a TSRlncRNA signature in glioma and 15 TSRlncRNAs that possess prognostic significance were identified, including AC010173.1, HOXA‐AS2, AC074286.1, AL592424.1, DRAIC, HOXC13‐AS, AC007938.1, AC010729.1, AC013472.3, AC093895.1, AC131097.4, AL606970.4, HOXC‐AS1, AGAP2‐AS1, and AC002456.1. This evidence concerns the gene AGAP2 and central nervous system cancer.