When dividing the patients into two groups according to the baseline median proportion of CD4+EOMES+T‐cells, we noticed that ALS patients with higher EOMES expression had higher progression rates either (1.0 [IQR: 0.7–1.9] vs. 0.4 [IQR: 0.3–0.9], p = 0.010). Here, CD4 is linked to amyotrophic lateral sclerosis.