Inflammation is associated with fibrosis, and we noted an age‐dependent increase in expression of platelet derived growth factor B (Pdgfb), platelet derived growth factor receptor β (Pdgfrb) α smooth muscle actin (Acta2), connective tissue growth factor (Ctgf), and collagen III (Col3a1) (~2.6‐fold, 1.5‐fold, 1.9‐fold, 7.8‐fold, and 2.8‐fold, respectively), suggesting increased fibroblast activation and matrix synthesis, consistent with age‐associated ovarian fibrosis (Amargant et al., 2020). The gene discussed is ACTA2; the disease is fibrosis.