TXNIP and myocardial infarction: Considering that the majority of previous studies focusing on TXNIP involved the use ofTxnip-KO animals or cells, we established theTxnip-KI mouse model to explore the role of TXNIP in post-MI fibrosis in a general TXNIP overexpression setting based on comparison of the results obtained from the WT,Txnip-KO, andTxnip-KI mice.