Finally, the relative expression of phosphorylated‐PI3K/total‐PI3K (p‐PI3K/t‐PI3K), phosphorylated‐Akt/total‐Akt (p‐Akt/t‐Akt), phosphorylated‐ERK/total‐ERK (p‐ERK/t‐ERK), phosphorylated‐P70S6K/total‐P70S6K (p‐P70S6K/t‐P70S6K), phosphorylated‐GSK3β/total‐GSK3β (p‐GSK3β/t‐GSK3β) and phosphorylated‐mTOR/total‐mTOR (p‐mTOR/t‐mTOR) further confirms the involvement of PI3K‐Akt–mTOR pathway in the development of NSCLC. Here, RPS6KB1 is linked to non-small cell lung carcinoma.