LGALS3 and atrial fibrillation: Another recent meta-analysis with more than 10,000 patients [23] came to four important conclusions: first, patients with AF had higher levels of Gal-3 compared with the sinus rhythm group (mean difference: −0.68 ng/mL, 95% confidence interval (CI): −0.92 to −0.44, p-value <0.00001).