On the other hand, thymic carcinomas bear a higher load of recurrent mutations within recognized cancer-associated genes, including but not limited to TP53, Cylindromatosis (CYLD), CDKN2A, BRCA1 associated protein 1 (BAP1), and polybromide 1 (PBRM1) (8). The gene discussed is CYLD; the disease is thymic carcinoma.