Transgenic CD8+ T cells expressing the 11Cαβ- or 2Cαβ-cTCR elicited IFNγ spot formation above background levels when co-cultured with the endogenously HLA-C*07:01+ melanoma cell lines D10, D41, the glioblastoma cell line MZ-257-GBM/HLA-C*07:01 and the lung cancer cell line MZ-LC-16/HLA-C*07:01 (Figure 5D). The gene discussed is CD8A; the disease is lung carcinoma.