Given the need to adhere to MHC haplotypes (since the DLK1 peptide is predicted to bind H-2 Db) and limited CRC transplantable models in C57BL/6 mice, we confirmed the anti-vascular effects of our αDC1-DLK1 vaccination scheme using a separate in vivo model incorporating LLC cells. The gene discussed is DLK1; the disease is colorectal carcinoma.