In addition, the expression of inflammatory cytokines, such as interferon gamma (IFN-γ), IL-6, interferon-inducible protein 10, eotaxin, MCP-1, macrophage inflammatory protein-1α (MIP-1α), and MIP-1β, was also elevated in the vitreous of patients with high myopia (29) as well as in highly myopic eyes with macular holes (MHs) (30). This evidence concerns the gene IFNG and macular holes.