NFKB1 and myopia: Overall, the potential biological mechanisms by which inflammation affects myopia may include the direct induction of scleral remodeling by inflammatory signaling pathways, including MAPK and NF-κB, and the indirect effects of the influence of inflammation on retinal and choroidal blood vasculature, interference with dopamine, modulation by extracellular vesicles (EVs) and regulation of the refractive index of the lens.