Hypertension-associated chronic inflammation, oxidative stress and hypertension-inducible mediators, such as vascular endothelial growth factors (VEGFs), hypoxic inducible factors (HIFs), the renin-angiotensin-aldosterone system (RAAS), and insulin-like growth factors (IGFs), might also play roles in tumor development [12]. The gene discussed is VEGFA; the disease is hypertensive disorder.