However, the metastatic burden in distant organs/tissues determined by ALU‐PCR was lower in the CD44 kd group compared with the control group (Fig. 3G, all values given are the median numbers of human TC/106 murine cells; P‐values were calculated using linear regression adjusting for tumor weight): lung CD44 kd 67 vs. control 183 (P < 0.001); liver CD44 kd 2.1 vs. control 12.5 (P = 0.027); bone marrow CD44 kd 0.8 vs. control 1.8 (P = 0.021). Here, CD44 is linked to neoplasm.