For example, CYP4A11, involved in NAFLD progression by inducing ROS-related lipid peroxidation and inflammation [81, 82], was significantly up-regulated in subgroups II and III; and CIDEC, a promotor of triglyceride accumulation [83, 84], was significantly up-regulated in subgroups I, II, and III. This evidence concerns the gene CYP4A11 and metabolic dysfunction-associated steatotic liver disease.