SLC5A2 and atrial fibrillation: There was no heterogeneity between instruments for the effect of SGLT2 inhibition on T2DM and AF (Q = 7.010, P = 0.536; Q = 1.780, P = 0.994), and no horizontal pleiotropy was detected (Egger intercept = 0.026, P = 0.115; Egger intercept = 0.012, P = 0.680).