Patients with JIA who reach remission had higher ITPA activity than those who do not reach remission (mean±standard deviation = 53.9±19.3 nmol vs 45.8±18.0 nmol IMP/h respectively, p-value logistic regression: 0.005, p-value Wilcoxon test: 0.003). The gene discussed is ITPA; the disease is juvenile idiopathic arthritis.