Monogenic autoinflammatory syndromes are those with identified genetic mutations, such as familial Mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), mevalonate kinase deficiency or hyperimmunoglobulin D syndrome HIDS, cryopyrin-associated periodic fever syndromes (CAPS). This evidence concerns the gene MVK and hyperinsulinemic hypoglycemia, familial, 4.