Instead, memory Treg-like cells (CD3+CD4+CD45RA-CD25-FoxP3+CTLA+) were enriched in SLE in both adults (2.33 [1.50-3.31]; 1.16 [0.94-1.71], p<0.001) and children (2.75 [1.90-4.36]; 1.28 [0.83-1.78], p<0.0001). This evidence concerns the gene CD4 and systemic lupus erythematosus.