The most common types of SAIDs were Chronic recurrent multifocal osteomyelitis (CRMO) (n=10), Cryopyrin associated Autoinflammatory syndromes (CAPS)(n=7), and PFAPA (n=7) followed by Blau syndrome (n=4), Otulin deficiency (n=3), Deficiency of Adenosine deaminase 2 (DADA2)(n=2), Pyogenic arthritis, pyoderma gangrenosum, acne (PAPA) syndrome(n=1), Majeed syndrome (n=1), TNF receptor associated periodic syndrome (TRAPS) (n=1), and Sideroblastic anemia, immunodeficiency, Periodic fevers, and developmental delay (SIFD) (n=1). Here, ADA2 is linked to immune system disorder.