In FMF patients, the levels of sFasL (attack 102.6±58.7 pg/mL vs attack-free 70.3±45.6 pg/mL; p=0.035) and Granzyme A (attack 3840.2±3273.7 pg/mL vs attack-free 2135.5±2283.1 pg/mL; p=0.038) were significantly increased during attack period and became comparable to the levels of HC during attack-free period. This evidence concerns the gene GZMA and familial Mediterranean fever.