STAT2 and viral infectious disease: Our analysis suggested that predicted inhibition of “viral infection”, “replication of virus” and “replication of RNA virus” could be associated with the aforementioned components of the innate immunity (RIG-1, STAT2, interferons) and DEAD-box protein 58 (DDX58) (Fig. 4)—a multifunctional protein responsible for recognition of double stranded RNA [43].