However, expression of all sialyltransferase-encoding genes (Fig. 7) was mostly downregulated by RVC and both RVA viruses with the exception of ST3Gal4 and the major Sialyl-Tn synthase—ST6GalNAc1 whose expression was marginally upregulated after infection with both RVA strains. The gene discussed is ST3GAL4; the disease is infection.