AFP and hepatocellular carcinoma: Takahiro Yamasaki et al. reported the prognostic factors in patients with advanced HCC receiving hepatic arterial infusion chemotherapy (HAIC) using low-dose cisplatin (CDDP) and 5-fluorouracil (5 - FU) with/without leucovorin (or isovorin), indicated that AFP level was a significant prognostic factor, and suggested that patients with a lower AFP level were suitable candidates for HAIC [23].