FOLH1 and posterior cortical atrophy: This study aimed to: (1) analyse the lesion-level patterns of progression in a cohort of biochemically recurrent (BCR) PCa patients undergoing standard-of-care treatment using several conventionally used imaging biomarkers in PSMA-PET, classifying the response heterogeneity among biomarkers, and (2) determine the correlation between radiographic patient-level patterns of progression, derived from matched lesion-level segmentations, and patient overall survival (OS) in the BCR setting.