SIRT1 and ischemia: Interestingly, SIRT1 was directly correlated with basal HBF (P = 0.0265), HBF post-heating (P = 0.0052), HBF post-ischemia (P = 0.0019), basal FBF (P = 0.0148), FBF post-heating (P = 0.0030), and FBF post-ischemia (P = 0.003).