Infection assays using VSVΔG-GFPpp showed that S proteins of the SARS-CoV-2 Hu-1, Delta and Omicron BA.1, BA.2, BA.4/5, XBB.1, and XBB.1.5 variants mediated infection of HEK293T cells expressing ACE2 receptors derived from civet, pangolin, racoon dog, camel, ferret, pig and intermediate horseshoe (Ra) bats (Fig. 2a). This evidence concerns the gene PROS1 and infection.