RACK1 and cancer: As a signaling hub, RACK1 has been associated with the activation of several cancer-related cellular signaling pathways, including PKC [34], receptor tyrosine kinase/PI3K/AKT, ERK/MAPK, integrin/Src/FAK [22], WNT/β-catenin, STAT3, and RhoA/Rho pathways [11, 12, 34–38].