CD4 and neoplasm: After adding anti-mouse-CD8 (aCD8) antibody and anti-mouse-CD4 (aCD4) antibody to block the CD4 and CD8 protein on T cells, only the aCD8 group and MHCII-GMCSF-Poly I:C treatment group illustrated the ability to delay tumour growth, and only the MHCII-GMCSF-Poly I:C treatment group showed a decrease in tumour volume after 22 days (Fig. 3h).