The methylation data of the NF-κB gene set obtained in pancancer through the GSCALite platform showed that the level of NF-κB gene methylation in a variety of cancers differed from that of normal samples, and the expression of MYD88, TNFRSF1A, TNFRSF1B, MAP3K14, and other genes had a strong correlation with the level of methylation, and all affected the survival of cancer patients, and the results were statistically different (Figure 2A). This evidence concerns the gene NFKB1 and cancer.