PGAM1 and clear cell renal carcinoma: Subsequently, we conducted a comprehensive assessment of various kidney cancers and discovered that the levels of phosphoglycerate mutase-1 (PGAM1) were elevated in both clear cell renal cell carcinoma (KIRC) and papillary renal cell carcinoma (KIRP) but reduced in chromophobe renal cell carcinoma (KICH) (Figure 2A).