PSEN1 and Alzheimer disease: Among 28 AD‐related genes, the ACHE, KLK6, APOC1, BCHE, and PSEN1 had strong negative, while KCNIP3, GSK3B, and SORL1 showed strong positive correlations with the T‐map of RMCS in AD compared to NC (p < .001; Figure 4c).