GLI1 and esophageal squamous cell carcinoma: rhCCL22 (50 ng/mL) treatment increased GDC‐0449 IC50 level in ESCC/wt Gli1 cells treatment (GDC‐0449 IC50 level in KYSE410/Gli1 wt cells was 19.08 ± 2.54 μM; in KYSE510/Gli1 wt cells, GDC‐0449 IC50 level was 16.91 ± 2.53 μM) (Figure 5A).