CCL22 and esophageal squamous cell carcinoma: We further assessed whether TAMs‐derived CCL22 could induce the anchorage‐independent growth of ESCC cells and found that CM from CCL22‐positive TAMs significantly stimulated the soft agar‐based colony formation of KYSE410 and KYSE510 cells, whereas the CM from CCL22‐negative TAMs not stimulated the soft agar‐based colony formation of KYSE410 and KYSE510 cells (Figure 1D).