TNF and systemic lupus erythematosus: For example, in non-lupus controls, modules such as IFN, plasma cell, IG chains, myeloid cell, and tumor necrosis factor (TNF) tended to have GSVA scores less than zero, whereas modules such as B cell, T cell, and T cell chains (TCRA, TCRAJ, TCRB, TCRD) tended to have GSVA scores greater than zero.