LncRNAs such as LOC107133214, LOC104974443 and LOC101906793 can regulate the expression of inflammatory and cell death-related mRNAs such as IL-6, NFKB1 and TNFAIP3 and participate in the process of mastitis through NOD-like receptor, TNF, MAPK and other signaling pathways. Here, NFKB1 is linked to mastitis.